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Lung immunoglobulin A immunity dysregulation in cystic fibrosis

BACKGROUND: In cystic fibrosis (CF), recurrent infections suggest impaired mucosal immunity but whether production of secretory immunoglobulin A (S-IgA) is impaired remains elusive. S-IgA is generated following polymeric immunoglobulin receptor (pIgR)-mediated transepithelial transport of dimeric (d...

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Detalles Bibliográficos
Autores principales: Collin, Amandine M., Lecocq, Marylène, Noel, Sabrina, Detry, Bruno, Carlier, François M., Aboubakar Nana, Frank, Bouzin, Caroline, Leal, Teresinha, Vermeersch, Marjorie, De Rose, Virginia, Regard, Lucile, Martin, Clémence, Burgel, Pierre-Régis, Hoton, Delphine, Verleden, Stijn, Froidure, Antoine, Pilette, Charles, Gohy, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495088/
https://www.ncbi.nlm.nih.gov/pubmed/32927272
http://dx.doi.org/10.1016/j.ebiom.2020.102974