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Lung immunoglobulin A immunity dysregulation in cystic fibrosis
BACKGROUND: In cystic fibrosis (CF), recurrent infections suggest impaired mucosal immunity but whether production of secretory immunoglobulin A (S-IgA) is impaired remains elusive. S-IgA is generated following polymeric immunoglobulin receptor (pIgR)-mediated transepithelial transport of dimeric (d...
Autores principales: | Collin, Amandine M., Lecocq, Marylène, Noel, Sabrina, Detry, Bruno, Carlier, François M., Aboubakar Nana, Frank, Bouzin, Caroline, Leal, Teresinha, Vermeersch, Marjorie, De Rose, Virginia, Regard, Lucile, Martin, Clémence, Burgel, Pierre-Régis, Hoton, Delphine, Verleden, Stijn, Froidure, Antoine, Pilette, Charles, Gohy, Sophie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495088/ https://www.ncbi.nlm.nih.gov/pubmed/32927272 http://dx.doi.org/10.1016/j.ebiom.2020.102974 |
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