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Host Porphobilinogen Deaminase Deficiency Confers Malaria Resistance in Plasmodium chabaudi but Not in Plasmodium berghei or Plasmodium falciparum During Intraerythrocytic Growth

An important component in host resistance to malaria infection are inherited mutations that give rise to abnormalities and deficiencies in erythrocyte proteins and enzymes. Understanding how such mutations confer protection against the disease may be useful for developing new treatment strategies. A...

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Detalles Bibliográficos
Autores principales: Schnider, Cilly Bernardette, Yang, Hao, Starrs, Lora, Ehmann, Anna, Rahimi, Farid, Di Pierro, Elena, Graziadei, Giovanna, Matthews, Kathryn, De Koning-Ward, Tania, Bauer, Denis C., Foote, Simon J., Burgio, Gaetan, McMorran, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495142/
https://www.ncbi.nlm.nih.gov/pubmed/33014890
http://dx.doi.org/10.3389/fcimb.2020.00464