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Suppression of c-Met-Overexpressing Tumors by a Novel c-Met/CD3 Bispecific Antibody
INTRODUCTION: Overexpression of c-Met, or hepatocyte growth factor (HGF) receptor, is commonly observed in tumor biopsies and often associated with poor patient survival, which makes HGF/c-Met pathway an attractive molecular target for cancer therapy. A number of antibody-based therapeutic strategie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495354/ https://www.ncbi.nlm.nih.gov/pubmed/32982167 http://dx.doi.org/10.2147/DDDT.S254117 |