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Single-Point Mutations within the Coxsackie B Virus Receptor-Binding Site Promote Resistance against Soluble Virus Receptor Traps

Coxsackie B viruses (CVB) cause a wide spectrum of diseases, ranging from mild respiratory syndromes and hand, foot, and mouth disease to life-threatening conditions, such as pancreatitis, myocarditis, and encephalitis. Previously, we and others found that the soluble virus receptor trap sCAR-Fc str...

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Detalles Bibliográficos
Autores principales: Pinkert, Sandra, Kopp, Anja, Brückner, Vanessa, Fechner, Henry, Beling, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495374/
https://www.ncbi.nlm.nih.gov/pubmed/32669334
http://dx.doi.org/10.1128/JVI.00952-20