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A multiple T cell epitope comprising DNA vaccine boosts the protective efficacy of Bacillus Calmette–Guérin (BCG) against Mycobacterium tuberculosis

BACKGROUND: Approximately 80% - 90% of individuals infected with latent Mycobacterium tuberculosis (Mtb) remain protected throughout their life-span. The release of unique, latent-phase antigens are known to have a protective role in the immune response against Mtb. Although the BCG vaccine has been...

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Detalles Bibliográficos
Autores principales: Maurya, Sudeep Kumar, Aqdas, Mohammad, Das, Deepjyoti Kumar, Singh, Sanpreet, Nadeem, Sajid, Kaur, Gurpreet, Agrewala, Javed Naim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495405/
https://www.ncbi.nlm.nih.gov/pubmed/32942991
http://dx.doi.org/10.1186/s12879-020-05372-1