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Antibody-Based Receptor Targeting Using an Fc-Binding Peptide-Dodecaborate Conjugate and Macropinocytosis Induction for Boron Neutron Capture Therapy

[Image: see text] Boron neutron capture therapy (BNCT) is a radiation method used for cancer therapy. Cellular uptake of boron-10 ((10)B) atoms induces cancer cell death by the generation of alpha particles and recoiling lithium-7 ((7)Li) nuclei when the cells are irradiated with low-energy thermal...

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Detalles Bibliográficos
Autores principales: Nakase, Ikuhiko, Aoki, Ayako, Sakai, Yuriko, Hirase, Shiori, Ishimura, Miki, Takatani-Nakase, Tomoka, Hattori, Yoshihide, Kirihata, Mitsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495456/
https://www.ncbi.nlm.nih.gov/pubmed/32954120
http://dx.doi.org/10.1021/acsomega.0c01377