Design and Development of Small-Molecule Arylaldoxime/5-Nitroimidazole Hybrids as Potent Inhibitors of MARK4: A Promising Approach for Target-Based Cancer Therapy

[Image: see text] Microtubule affinity-regulating kinase 4 (MARK4), a member of the serine/threonine kinase family, is an emerging therapeutic target in anticancer drug discovery paradigm due to its involvement in regulation of microtubule dynamics, cell cycle regulation, and cancer progression. The...

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Detalles Bibliográficos
Autores principales: Peerzada, Mudasir Nabi, Khan, Parvez, Khan, Nashrah Sharif, Avecilla, Fernando, Siddiqui, Shadab Miyan, Hassan, Md. Imtaiyaz, Azam, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495461/
https://www.ncbi.nlm.nih.gov/pubmed/32954123
http://dx.doi.org/10.1021/acsomega.0c01703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495461/
https://www.ncbi.nlm.nih.gov/pubmed/32954123
http://dx.doi.org/10.1021/acsomega.0c01703

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