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Design and Development of Small-Molecule Arylaldoxime/5-Nitroimidazole Hybrids as Potent Inhibitors of MARK4: A Promising Approach for Target-Based Cancer Therapy
[Image: see text] Microtubule affinity-regulating kinase 4 (MARK4), a member of the serine/threonine kinase family, is an emerging therapeutic target in anticancer drug discovery paradigm due to its involvement in regulation of microtubule dynamics, cell cycle regulation, and cancer progression. The...
Autores principales: | Peerzada, Mudasir Nabi, Khan, Parvez, Khan, Nashrah Sharif, Avecilla, Fernando, Siddiqui, Shadab Miyan, Hassan, Md. Imtaiyaz, Azam, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495461/ https://www.ncbi.nlm.nih.gov/pubmed/32954123 http://dx.doi.org/10.1021/acsomega.0c01703 |
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