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Small-residue packing motifs modulate the structure and function of a minimal de novo membrane protein

Alpha-helical integral membrane proteins contain conserved sequence motifs that are known to be important in helix packing. These motifs are a promising starting point for the construction of artificial proteins, but their potential has not yet been fully explored. Here, we study the impact of intro...

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Detalles Bibliográficos
Autores principales: Curnow, Paul, Hardy, Benjamin J., Dufour, Virginie, Arthur, Christopher J., Stenner, Richard, Hodgson, Lorna R., Verkade, Paul, Williams, Christopher, Shoemark, Deborah K., Sessions, Richard B., Crump, Matthew P., Jones, Michael R., Anderson, J. L. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495484/
https://www.ncbi.nlm.nih.gov/pubmed/32938984
http://dx.doi.org/10.1038/s41598-020-71585-8