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Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats

BACKGROUND: Parkinson’s disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical and quality of life issues and are present in 90% of PD patients; yet the underlyin...

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Detalles Bibliográficos
Autores principales: Kelm-Nelson, Cynthia A., Gammie, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495669/
https://www.ncbi.nlm.nih.gov/pubmed/32942992
http://dx.doi.org/10.1186/s12864-020-07037-4