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Accessing the Ene–Imine Motif in 1H-Isoindole, Thienopyrrole, and Thienopyridine Building Blocks

[Image: see text] A pathway to a range of diverse heterocycles was developed using a nucleophilic cyclization strategy. Lactams and ene-imines are accessed in a few steps from a common precursor, and these moieties are further elaborated to directly provide pyrroles or pyridines with extended conjug...

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Detalles Bibliográficos
Autores principales: Fillmore, Brandon C., Price, Jayden, Dean, Ryan, Brown, Amy A., Decken, Andreas, Eisler, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495751/
https://www.ncbi.nlm.nih.gov/pubmed/32954140
http://dx.doi.org/10.1021/acsomega.0c02282