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A learning-based method for drug-target interaction prediction based on feature representation learning and deep neural network

BACKGROUND: Drug-target interaction prediction is of great significance for narrowing down the scope of candidate medications, and thus is a vital step in drug discovery. Because of the particularity of biochemical experiments, the development of new drugs is not only costly, but also time-consuming...

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Detalles Bibliográficos
Autores principales: Peng, Jiajie, Li, Jingyi, Shang, Xuequn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495825/
https://www.ncbi.nlm.nih.gov/pubmed/32938374
http://dx.doi.org/10.1186/s12859-020-03677-1