Prediction of hot spots in protein–DNA binding interfaces based on supervised isometric feature mapping and extreme gradient boosting

BACKGROUND: Identification of hot spots in protein-DNA interfaces provides crucial information for the research on protein-DNA interaction and drug design. As experimental methods for determining hot spots are time-consuming, labor-intensive and expensive, there is a need for developing reliable com...

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Detalles Bibliográficos
Autores principales: Li, Ke, Zhang, Sijia, Yan, Di, Bin, Yannan, Xia, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495874/
https://www.ncbi.nlm.nih.gov/pubmed/32938395
http://dx.doi.org/10.1186/s12859-020-03683-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495874/
https://www.ncbi.nlm.nih.gov/pubmed/32938395
http://dx.doi.org/10.1186/s12859-020-03683-3

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