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GPU acceleration of Darwin read overlapper for de novo assembly of long DNA reads

BACKGROUND: In Overlap-Layout-Consensus (OLC) based de novo assembly, all reads must be compared with every other read to find overlaps. This makes the process rather slow and limits the practicality of using de novo assembly methods at a large scale in the field. Darwin is a fast and accurate read...

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Detalles Bibliográficos
Autores principales: Ahmed, Nauman, Qiu, Tong Dong, Bertels, Koen, Al-Ars, Zaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495891/
https://www.ncbi.nlm.nih.gov/pubmed/32938392
http://dx.doi.org/10.1186/s12859-020-03685-1