Cargando…
Computationally identifying hot spots in protein-DNA binding interfaces using an ensemble approach
BACKGROUND: Protein-DNA interaction governs a large number of cellular processes, and it can be altered by a small fraction of interface residues, i.e., the so-called hot spots, which account for most of the interface binding free energy. Accurate prediction of hot spots is critical to understand th...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495898/ https://www.ncbi.nlm.nih.gov/pubmed/32938375 http://dx.doi.org/10.1186/s12859-020-03675-3 |