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FTY720 Protects Against Ischemia–Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model

Injury due to brain ischemia followed by reperfusion (I/R) may be an important therapeutic target in the era of thrombectomy. FTY720, a widely known sphingosine-1-phosphate receptor agonist, exerts various neuroprotective effects. The aim of this study was to examine the protective effect of FTY720...

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Detalles Bibliográficos
Autores principales: Wang, Zifeng, Higashikawa, Kei, Yasui, Hironobu, Kuge, Yuji, Ohno, Yusuke, Kihara, Akio, Midori, Yenari A., Houkin, Kiyohiro, Kawabori, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496052/
https://www.ncbi.nlm.nih.gov/pubmed/32103462
http://dx.doi.org/10.1007/s12975-020-00789-x