Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor

Pathogenic bacteria of the Burkholderia pseudomallei group cause severe infectious diseases such as glanders and melioidosis. Malleicyprols were identified as important bacterial virulence factors, yet the biosynthetic origin of their cyclopropanol warhead has remained enigmatic. By a combination of...

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Detalles Bibliográficos
Autores principales: Trottmann, Felix, Ishida, Keishi, Franke, Jakob, Stanišić, Aleksa, Ishida‐Ito, Mie, Kries, Hajo, Pohnert, Georg, Hertweck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496086/
https://www.ncbi.nlm.nih.gov/pubmed/32314848
http://dx.doi.org/10.1002/anie.202003958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496086/
https://www.ncbi.nlm.nih.gov/pubmed/32314848
http://dx.doi.org/10.1002/anie.202003958

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