Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans

Fungal infections are a global issue affecting over 150 million people worldwide annually, with 750 000 of these caused by invasive Candida infections. Azole drugs are the frontline treatment against fungal infections; however, resistance to current azole antifungals in C. albicans poses a threat to...

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Detalles Bibliográficos
Autores principales: Binjubair, Faizah A., Parker, Josie E., Warrilow, Andrew G., Puri, Kalika, Braidley, Peter J., Tatar, Esra, Kelly, Steven L., Kelly, Diane E., Simons, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496091/
https://www.ncbi.nlm.nih.gov/pubmed/32459374
http://dx.doi.org/10.1002/cmdc.202000250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496091/
https://www.ncbi.nlm.nih.gov/pubmed/32459374
http://dx.doi.org/10.1002/cmdc.202000250

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