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Enantioselective Synthesis of 3‐Fluorochromanes via Iodine(I)/Iodine(III) Catalysis

The chromane nucleus is common to a plenum of bioactive small molecules where it is frequently oxidized at position 3. Motivated by the importance of this position in conferring efficacy, and the prominence of bioisosterism in drug discovery, an iodine(I)/iodine(III) catalysis strategy to access ena...

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Detalles Bibliográficos
Autores principales: Sarie, Jérôme C., Thiehoff, Christian, Neufeld, Jessica, Daniliuc, Constantin G., Gilmour, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496101/
https://www.ncbi.nlm.nih.gov/pubmed/32347605
http://dx.doi.org/10.1002/anie.202005181