Reconciling Electrostatic and n→π* Orbital Contributions in Carbonyl Interactions

Interactions between carbonyl groups are prevalent in protein structures. Earlier investigations identified dominant electrostatic dipolar interactions, while others implicated lone pair n→π* orbital delocalisation. Here these observations are reconciled. A combined experimental and computational ap...

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Detalles Bibliográficos
Autores principales: Muchowska, Kamila B., Pascoe, Dominic J., Borsley, Stefan, Smolyar, Ivan V., Mati, Ioulia K., Adam, Catherine, Nichol, Gary S., Ling, Kenneth B., Cockroft, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496118/
https://www.ncbi.nlm.nih.gov/pubmed/32485046
http://dx.doi.org/10.1002/anie.202005739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496118/
https://www.ncbi.nlm.nih.gov/pubmed/32485046
http://dx.doi.org/10.1002/anie.202005739

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