Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events

A mycoplasma contamination event in a biomanufacturing facility can result in costly cleanups and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and penetrate the standard 0.2‐µm filters used in the clarification of harvested cell...

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Detalles Bibliográficos
Autores principales: Fratz‐Berilla, Erica J., Angart, Phillip, Graham, Ryan J., Powers, David N., Mohammad, Adil, Kohnhorst, Casey, Faison, Talia, Velugula‐Yellela, Sai Rashmika, Trunfio, Nicholas, Agarabi, Cyrus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496122/
https://www.ncbi.nlm.nih.gov/pubmed/32436993
http://dx.doi.org/10.1002/bit.27436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496122/
https://www.ncbi.nlm.nih.gov/pubmed/32436993
http://dx.doi.org/10.1002/bit.27436

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