Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare, inherited cholestatic liver disorders that manifest in infants and children and are associated with impaired bile flow (ie cholestasis), pruritus and potentially fatal liver disease. There are no effective or...

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Detalles Bibliográficos
Autores principales: Kamath, Binita M., Stein, Philip, Houwen, Roderick H. J., Verkade, Henkjan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://www.ncbi.nlm.nih.gov/pubmed/32492754
http://dx.doi.org/10.1111/liv.14553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://www.ncbi.nlm.nih.gov/pubmed/32492754
http://dx.doi.org/10.1111/liv.14553

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