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What is the evidence for interactions between filaggrin null mutations and environmental exposures in the aetiology of atopic dermatitis? A systematic review

BACKGROUND: Epidemiological studies indicate that gene–environment interactions play a role in atopic dermatitis (AD). OBJECTIVES: To review the evidence for gene–environment interactions in AD aetiology, focusing on filaggrin (FLG) loss‐of‐function mutations. METHODS: A systematic search from incep...

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Detalles Bibliográficos
Autores principales: Blakeway, H., Van‐de-Velde, V., Allen, V.B., Kravvas, G., Palla, L., Page, M.J., Flohr, C., Weller, R.B., Irvine, A.D., McPherson, T., Roberts, A., Williams, H.C., Reynolds, N., Brown, S.J., Paternoster, L., Langan, S.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496176/
https://www.ncbi.nlm.nih.gov/pubmed/31794059
http://dx.doi.org/10.1111/bjd.18778