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A Primary Evaluation of Potential Small‐Molecule Inhibitors of the Astacin Metalloproteinase Ovastacin, a Novel Drug Target in Female Infertility Treatment

Despite huge progress in hormonal therapy and improved in vitro fertilization methods, the success rates in infertility treatment are still limited. A recently discovered mechanism revealed the interplay between the plasma protein fetuin‐B and the cortical granule‐based proteinase ovastacin to be a...

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Detalles Bibliográficos
Autores principales: Körschgen, Hagen, Jäger, Christian, Tan, Kathrin, Buchholz, Mirko, Stöcker, Walter, Ramsbeck, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496240/
https://www.ncbi.nlm.nih.gov/pubmed/32946206
http://dx.doi.org/10.1002/cmdc.202000397