Reduced iron export associated with hepcidin resistance can explain the iron overload spectrum in ferroportin disease

BACKGROUND & AIMS: Ferroportin disease (FD) and hemochromatosis type 4 (HH4) are associated with variants in the ferroportin‐encoding gene SLC40A1. Both phenotypes are characterized by iron overload despite being caused by distinct variants that either mediate reduced cellular iron export in FD...

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Detalles Bibliográficos
Autores principales: Viveiros, André, Panzer, Marlene, Baumgartner, Nadja, Schaefer, Benedikt, Finkenstedt, Armin, Henninger, Benjamin, Theurl, Igor, Nachbaur, Karin, Weiss, Günter, Haubner, Roland, Decristoforo, Clemens, Tilg, Herbert, Zoller, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Genetics and Rare Liver Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496278/
https://www.ncbi.nlm.nih.gov/pubmed/32450003
http://dx.doi.org/10.1111/liv.14539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496278/
https://www.ncbi.nlm.nih.gov/pubmed/32450003
http://dx.doi.org/10.1111/liv.14539

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