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Ligand‐Enabled γ‐C(sp(3))−H Olefination of Free Carboxylic Acids
We report the ligand‐enabled C−H activation/olefination of free carboxylic acids in the γ‐position. Through an intramolecular Michael addition, δ‐lactones are obtained as products. Two distinct ligand classes are identified that enable the challenging palladium‐catalyzed activation of free carboxyli...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496353/ https://www.ncbi.nlm.nih.gov/pubmed/32250014 http://dx.doi.org/10.1002/anie.202002362 |