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Ligand‐Enabled γ‐C(sp(3))−H Olefination of Free Carboxylic Acids

We report the ligand‐enabled C−H activation/olefination of free carboxylic acids in the γ‐position. Through an intramolecular Michael addition, δ‐lactones are obtained as products. Two distinct ligand classes are identified that enable the challenging palladium‐catalyzed activation of free carboxyli...

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Detalles Bibliográficos
Autores principales:	Ghosh, Kiron Kumar, Uttry, Alexander, Mondal, Arup, Ghiringhelli, Francesca, Wedi, Philipp, van Gemmeren, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496353/ https://www.ncbi.nlm.nih.gov/pubmed/32250014 http://dx.doi.org/10.1002/anie.202002362

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