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Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages
Derivatives of 4‐aminomethyl‐l‐phenylalanine with aromatic oligoamide foldamers as sidechain appendages were successfully charged on tRNA by means of flexizymes. Their subsequent incorporation both at the C‐terminus of, and within, peptide sequences by the ribosome, was demonstrated. These results e...
Autores principales: | Tsiamantas, Christos, Kwon, Sunbum, Rogers, Joseph M., Douat, Céline, Huc, Ivan, Suga, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496375/ https://www.ncbi.nlm.nih.gov/pubmed/31894626 http://dx.doi.org/10.1002/anie.201914654 |
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