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High levels of dd‐cfDNA identify patients with TCMR 1A and borderline allograft rejection at elevated risk of graft injury

The clinical importance of subclinical, early T cell–mediated rejection (Banff TCMR 1A and borderline lesions) remains unclear, due, in part to the fact that histologic lesions used to characterize early TCMR can be nonspecific. Donor‐derived cell‐free DNA (dd‐cfDNA) is an important molecular marker...

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Detalles Bibliográficos
Autores principales: Stites, Erik, Kumar, Dhiren, Olaitan, Oyedolamu, John Swanson, Sidney, Leca, Nicolae, Weir, Matthew, Bromberg, Jonathan, Melancon, Joseph, Agha, Irfan, Fattah, Hasan, Alhamad, Tarek, Qazi, Yasir, Wiseman, Alexander, Gupta, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496411/
https://www.ncbi.nlm.nih.gov/pubmed/32056331
http://dx.doi.org/10.1111/ajt.15822