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An autoinhibitory mechanism controls RNA‐binding activity of the nitrate‐sensing protein NasR

The ANTAR domain harnesses RNA‐binding activity to promote transcription attenuation. Although several ANTAR proteins have been analyzed by high‐resolution structural analyses, the residues involved in RNA‐recognition and transcription attenuation have not been identified. Nor is it clear how signal...

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Detalles Bibliográficos
Autores principales: Goodson, Jonathan R., Zhang, Christopher, Trettel, Daniel, Ailinger, Heather E., Lee, Priscilla E., Spirito, Catherine M., Winkler, Wade C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496416/
https://www.ncbi.nlm.nih.gov/pubmed/32314426
http://dx.doi.org/10.1111/mmi.14517