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The contribution of Parkin, PINK1 and DJ‐1 genes to selective neuronal degeneration in Parkinson's disease

Parkinson's disease (PD) is characterised by selective and severe degeneration of the substantia nigra pars compacta and the locus coeruleus (LC), which underlies the most prominent symptoms. Although α‐synuclein accumulation has long been established to play a causal role in the disease, it al...

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Detalles Bibliográficos
Autores principales: van der Vlag, Marc, Havekes, Robbert, Heckman, Pim R. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496448/
https://www.ncbi.nlm.nih.gov/pubmed/31991026
http://dx.doi.org/10.1111/ejn.14689