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Common Variants Coregulate Expression of GBA and Modifier Genes to Delay Parkinson's Disease Onset
BACKGROUND: GBA mutations are numerically the most significant genetic risk factor for Parkinson's disease (PD), yet these mutations have low penetrance, suggesting additional mechanisms. OBJECTIVES: The objective of this study was to determine if the penetrance of GBA in PD can be explained by...
Autores principales: | Schierding, William, Farrow, Sophie, Fadason, Tayaza, Graham, Oscar E.E., Pitcher, Toni L., Qubisi, Sara, Davidson, Alan J., Perry, Jo K., Anderson, Tim J., Kennedy, Martin A., Cooper, Antony, O'Sullivan, Justin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496525/ https://www.ncbi.nlm.nih.gov/pubmed/32557794 http://dx.doi.org/10.1002/mds.28144 |
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