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Template‐Directed Copying of RNA by Non‐enzymatic Ligation

The non‐enzymatic replication of the primordial genetic material is thought to have enabled the evolution of early forms of RNA‐based life. However, the replication of oligonucleotides long enough to encode catalytic functions is problematic due to the low efficiency of template copying with mononuc...

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Detalles Bibliográficos
Autores principales: Zhou, Lijun, O'Flaherty, Derek K., Szostak, Jack W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496532/
https://www.ncbi.nlm.nih.gov/pubmed/32558121
http://dx.doi.org/10.1002/anie.202004934