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Template‐Directed Copying of RNA by Non‐enzymatic Ligation
The non‐enzymatic replication of the primordial genetic material is thought to have enabled the evolution of early forms of RNA‐based life. However, the replication of oligonucleotides long enough to encode catalytic functions is problematic due to the low efficiency of template copying with mononuc...
Autores principales: | Zhou, Lijun, O'Flaherty, Derek K., Szostak, Jack W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496532/ https://www.ncbi.nlm.nih.gov/pubmed/32558121 http://dx.doi.org/10.1002/anie.202004934 |
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