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Pressure Sensitivity of SynGAP/PSD‐95 Condensates as a Model for Postsynaptic Densities and Its Biophysical and Neurological Ramifications

Biomolecular condensates consisting of proteins and nucleic acids can serve critical biological functions, so that some condensates are referred as membraneless organelles. They can also be disease‐causing, if their assembly is misregulated. A major physicochemical basis of the formation of biomolec...

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Detalles Bibliográficos
Autores principales: Cinar, Hasan, Oliva, Rosario, Lin, Yi‐Hsuan, Chen, Xudong, Zhang, Mingjie, Chan, Hue Sun, Winter, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496680/
https://www.ncbi.nlm.nih.gov/pubmed/31910298
http://dx.doi.org/10.1002/chem.201905269