Cargando…

Photocatalytic α‐Tertiary Amine Synthesis via C−H Alkylation of Unmasked Primary Amines

A practical, catalytic entry to α,α,α‐trisubstituted (α‐tertiary) primary amines by C−H functionalisation has long been recognised as a critical gap in the synthetic toolbox. We report a simple and scalable solution to this problem that does not require any in situ protection of the amino group and...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryder, Alison S. H., Cunningham, William B., Ballantyne, George, Mules, Tom, Kinsella, Anna G., Turner‐Dore, Jacob, Alder, Catherine M., Edwards, Lee J., McKay, Blandine S. J., Grayson, Matthew N., Cresswell, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496683/
https://www.ncbi.nlm.nih.gov/pubmed/32391968
http://dx.doi.org/10.1002/anie.202005294