Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice

Disruption of the circadian cycle is strongly associated with metabolic imbalance and reduced longevity in humans. Also, rodent models of circadian arrhythmia, such as the constitutive knockout of the clock gene Bmal1, leads to metabolic disturbances and early death. Although astrocyte clock regulat...

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Detalles Bibliográficos
Autores principales: Barca‐Mayo, Olga, Boender, Arjen J., Armirotti, Andrea, De Pietri Tonelli, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496695/
https://www.ncbi.nlm.nih.gov/pubmed/31833591
http://dx.doi.org/10.1002/glia.23764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496695/
https://www.ncbi.nlm.nih.gov/pubmed/31833591
http://dx.doi.org/10.1002/glia.23764

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