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RS‐1 enhances CRISPR‐mediated targeted knock‐in in bovine embryos

Targeted knock‐in (KI) can be achieved in embryos by clustered regularly interspaced short palindromic repeats (CRISPR)‐assisted homology directed repair (HDR). However, HDR efficiency is constrained by the competition of nonhomologous end joining. The objective of this study was to explore whether...

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Detalles Bibliográficos
Autores principales: Lamas‐Toranzo, I., Martínez‐Moro, A., O´Callaghan, E., Millán‐Blanca, G., Sánchez, J.M., Lonergan, P., Bermejo‐Álvarez, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496720/
https://www.ncbi.nlm.nih.gov/pubmed/32227559
http://dx.doi.org/10.1002/mrd.23341