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Extracellular vesicles: where the amyloid precursor protein carboxyl‐terminal fragments accumulate and amyloid‐β oligomerizes

Pleiotropic roles are proposed for brain extracellular vesicles (EVs) in the development of Alzheimer's disease (AD). Our previous studies have suggested a beneficial role for EVs in AD, where the endosomal system in vulnerable neurons is compromised, contributing to the removal of accumulated...

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Detalles Bibliográficos
Autores principales: Pérez‐González, Rocío, Kim, Yohan, Miller, Chelsea, Pacheco‐Quinto, Javier, Eckman, Elizabeth A., Levy, Efrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496786/
https://www.ncbi.nlm.nih.gov/pubmed/32772431
http://dx.doi.org/10.1096/fj.202000823R