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The N‐terminal and C‐terminal halves of histone H2A.Z independently function in nucleosome positioning and stability

Nucleosome positioning and stability affect gene regulation in eukaryotic chromatin. Histone H2A.Z is an evolutionally conserved histone variant that forms mobile and unstable nucleosomes in vivo and in vitro. In the present study, we reconstituted nucleosomes containing human H2A.Z.1 mutants, in wh...

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Detalles Bibliográficos
Autores principales: Sato, Shoko, Tanaka, Naoki, Arimura, Yasuhiro, Kujirai, Tomoya, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496805/
https://www.ncbi.nlm.nih.gov/pubmed/32500630
http://dx.doi.org/10.1111/gtc.12791