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USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating the Wnt/β‐catenin pathway via Axin1 deubiquitination

Colorectal cancer (CRC) is the leading cause of cancer death, and its 5‐year survival rate remains unsatisfactory. Recent studies have revealed that ubiquitin‐specific protease 44 (USP44) is a cancer suppressor or oncogene depending on the type of neoplasm. However, its role in CRC remains unclear....

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Detalles Bibliográficos
Autores principales: Huang, Tong, Zhang, Qingquan, Ren, Wei, Yan, Bing, Yi, Liang, Tang, Tielun, Lin, Hai, Zhang, Yongjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496820/
https://www.ncbi.nlm.nih.gov/pubmed/32285989
http://dx.doi.org/10.1002/cbin.11358