Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production

Male development, fertility, and lifelong health are all androgen‐dependent. Approximately 95% of circulating testosterone is synthesized by the testis and the final step in this canonical pathway is controlled by the activity of the hydroxysteroid‐dehydrogenase‐17‐beta‐3 (HSD17B3). To determine the...

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Detalles Bibliográficos
Autores principales: Rebourcet, Diane, Mackay, Rosa, Darbey, Annalucia, Curley, Michael K., Jørgensen, Anne, Frederiksen, Hanne, Mitchell, Rod T., O’Shaughnessy, Peter J., Nef, Serge, Smith, Lee B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496839/
https://www.ncbi.nlm.nih.gov/pubmed/32557858
http://dx.doi.org/10.1096/fj.202000361R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496839/
https://www.ncbi.nlm.nih.gov/pubmed/32557858
http://dx.doi.org/10.1096/fj.202000361R

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