Monitoring Dicer‐Mediated miRNA‐21 Maturation and Ago2 Loading by a Dual‐Colour FIT PNA Probe Set

The inhibition of micro RNA (miRNA) maturation by Dicer and loading matured miRNAs into the RNA‐induced silencing complex (RISC) is envisioned as a modality for treatment of cancer. Existing methods for evaluating maturation either focus on the conversion of modified precursors or detect mature miRN...

Descripción completa

Detalles Bibliográficos
Autores principales: Loibl, Natalia, Arenz, Christoph, Seitz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496889/
https://www.ncbi.nlm.nih.gov/pubmed/32270536
http://dx.doi.org/10.1002/cbic.202000173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496889/
https://www.ncbi.nlm.nih.gov/pubmed/32270536
http://dx.doi.org/10.1002/cbic.202000173

Ejemplares similares