Pharmacokinetics and Safety of a Single Oral Dose of Peficitinib (ASP015K) in Japanese Subjects With Normal and Impaired Hepatic Function

Peficitinib (ASP015K) is a novel Janus kinase inhibitor developed for the treatment of rheumatoid arthritis (RA). The impact of hepatic impairment on the peficitinib pharmacokinetic (PK) and safety profile was investigated in non‐RA subjects (n = 24) in an open‐label, parallel‐group, multicenter com...

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Detalles Bibliográficos
Autores principales: Miyatake, Daisuke, Shibata, Tomohisa, Toyoshima, Junko, Kaneko, Yuichiro, Oda, Kazuo, Nishimura, Tetsuya, Katashima, Masataka, Sakaki, Masashi, Inoue, Kazuaki, Ito, Takayoshi, Uchida, Naoki, Furihata, Kenichi, Urae, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496893/
https://www.ncbi.nlm.nih.gov/pubmed/31833184
http://dx.doi.org/10.1002/cpdd.751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496893/
https://www.ncbi.nlm.nih.gov/pubmed/31833184
http://dx.doi.org/10.1002/cpdd.751

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