Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug‐resistant temporal lobe epilepsy and comorbid depression

OBJECTIVE: Depressive disorders are common among about 50% of the patients with drug‐resistant temporal lobe epilepsy (TLE). The underlying etiology remains elusive, but hypothalamus‐pituitary‐adrenal (HPA) axis activation due to changes in glucocorticoid receptor (GR) protein expression could play...

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Detalles Bibliográficos
Autores principales: D’Alessio, Luciana, Mesarosova, Lucia, Anink, Jasper J., Kochen, Silvia, Solís, Patricia, Oddo, Silvia, Konopka, Hector, Iyer, Anand M., Mühlebner, Angelika, Lucassen, Paul J., Aronica, Eleonora, van Vliet, Erwin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full‐length Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496961/
https://www.ncbi.nlm.nih.gov/pubmed/32652588
http://dx.doi.org/10.1111/epi.16598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496961/
https://www.ncbi.nlm.nih.gov/pubmed/32652588
http://dx.doi.org/10.1111/epi.16598

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