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Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug‐resistant temporal lobe epilepsy and comorbid depression
OBJECTIVE: Depressive disorders are common among about 50% of the patients with drug‐resistant temporal lobe epilepsy (TLE). The underlying etiology remains elusive, but hypothalamus‐pituitary‐adrenal (HPA) axis activation due to changes in glucocorticoid receptor (GR) protein expression could play...
Autores principales: | D’Alessio, Luciana, Mesarosova, Lucia, Anink, Jasper J., Kochen, Silvia, Solís, Patricia, Oddo, Silvia, Konopka, Hector, Iyer, Anand M., Mühlebner, Angelika, Lucassen, Paul J., Aronica, Eleonora, van Vliet, Erwin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496961/ https://www.ncbi.nlm.nih.gov/pubmed/32652588 http://dx.doi.org/10.1111/epi.16598 |
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