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On‐Chip Neo‐Glycopeptide Synthesis for Multivalent Glycan Presentation

Single glycan–protein interactions are often weak, such that glycan binding partners commonly utilize multiple, spatially defined binding sites to enhance binding avidity and specificity. Current array technologies usually neglect defined multivalent display. Laser‐based array synthesis technology a...

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Detalles Bibliográficos
Autores principales: Mende, Marco, Tsouka, Alexandra, Heidepriem, Jasmin, Paris, Grigori, Mattes, Daniela S., Eickelmann, Stephan, Bordoni, Vittorio, Wawrzinek, Robert, Fuchsberger, Felix F., Seeberger, Peter H., Rademacher, Christoph, Delbianco, Martina, Mallagaray, Alvaro, Loeffler, Felix F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496964/
https://www.ncbi.nlm.nih.gov/pubmed/32315099
http://dx.doi.org/10.1002/chem.202001291