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Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model

BACKGROUND: Immune challenge is known to increase heat stroke risk, although the mechanism of this increased risk is unclear. OBJECTIVES: We sought to understand the effect of immune challenge on heat stroke pathology. PATIENTS/METHODS: Using a mouse model of classic heat stroke, we examined the imp...

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Detalles Bibliográficos
Autores principales: Proctor, Elizabeth A., Dineen, Shauna M., Van Nostrand, Stephen C., Kuhn, Madison K., Barrett, Christopher D., Brubaker, Douglas K., Yaffe, Michael B., Lauffenburger, Douglas A., Leon, Lisa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496969/
https://www.ncbi.nlm.nih.gov/pubmed/32367690
http://dx.doi.org/10.1111/jth.14875