Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2

N‐Acetyltransferases play critical roles in the deactivation and clearance of xenobiotics, including clinical drugs. NAT2 has been classified as an arylamine N‐acetyltransferase that mainly converts aromatic amines, hydroxylamines, and hydrazines. Herein, we demonstrate that the human arylamine N‐ac...

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Detalles Bibliográficos
Autores principales: Conway, Louis P., Rendo, Veronica, Correia, Mário S. P., Bergdahl, Ingvar A., Sjöblom, Tobias, Globisch, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497018/
https://www.ncbi.nlm.nih.gov/pubmed/32497306
http://dx.doi.org/10.1002/anie.202005915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497018/
https://www.ncbi.nlm.nih.gov/pubmed/32497306
http://dx.doi.org/10.1002/anie.202005915

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